Find a Clinical Trial

Find a Clinical Trial

All Clinical Trials (newest first)

Full Study Title: Hematopoietic Stem Cell Transplant for Fanconi Anemia (FA) Summary The trial proposed is a single arm phase II treatment protocol designed to examine engraftment, toxicity, graft-versus-host disease, and ultimate disease-free survival following a novel cytoreductive regimen including busulfan, cyclophosphamide and fludarabine and anti-thymocyte globulin (ATG-...

Full Study Title: Targeted, Highly Sensitive, Non-Invasive Cardiac Transplant Rejection Monitoring Summary The investigator's primary goal is to quantitatively detect donor-specific DNA in plasma of organ transplant recipients. The investigator believe's that donor specific DNA can be isolated and quantified from transplant recipient serum. The investigator hypothesizes that...

Full Study Title: Family Health History in Diverse Care Settings Summary The outcome of this research will be a demonstration that family health history (FHH) risk data can be used efficiently to deliver more effective healthcare in geographically and ethnically diverse clinical care environments. Although FHH is a...

Full Study Title: Ticagrelor in Severe Community Acquired Pneumonia (TCAP) Summary The purpose of this study is to determine if the drug ticagrelor will be an effective treatment for patients with severe community acquired pneumonia. The primary objective is to reduce all-cause mortality in the ticagrelor group compared...

Full Study Title: A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) Summary This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications. Participant Eligibility Inclusion Criteria: Disorders affecting the hematopoietic...

Full Study Title: Efficacy of Isradipine in Early Parkinson Disease Summary The purpose of the study is to determine whether treatment with isradipine is effective in slowing the progression of Parkinson disease disability. Participant Eligibility Inclusion Criteria: Subjects with early idiopathic PD (presence of at least two out of three cardinal...

Full Study Title: Phase 2 Study of Montelukast for the Treatment of Sickle Cell Anemia Summary In this feasibility trial, the investigators will compare participants treated with montelukast and hydroxyurea to those treated with placebo and hydroxyurea for a total of 8 weeks. Participant Eligibility Inclusion Criteria: Diagnosis of HbSS, or...

Full Study Title: Phase III, Open-labeled, Multicenter Study of the Safety and Efficacy of Brincidofovir (CMX001) in the Treatment of Early Versus Late Adenovirus Infection (CMX001 Adv) Summary This is a multicenter study of Brincidofovir (CMX001) (BCV) administered twice weekly (BIW) for the treatment of AdV infection detected...

Full Study Title: Tocilizumab in the Treatment of Refractory Polymyositis and Dermatomyositis (TIM) Summary The purpose of this multi-center pilot study is to determine if the drug tocilizumab (Actemra) is effective in the treatment of patients with refractory adult polymyositis (PM) and dermatomyositis (DM). Participant Eligibility Inclusion Criteria: Patients will be...

Full Study Title: Study of Modified Docetaxel, Cisplatin, and Fluorouracil (mDCF) in Unresectable or Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma Summary Chemotherapy given together is a standard way to treat your cancer. One standard treatment includes a combination of docetaxel, cisplatin, and fluorouracil. However, the original combination of...

The purpose of this study is to use a unique eye imaging technique to compare changes in the retina in healthy volunteers to individuals with memory loss....

The purpose of this registry is to collect data on progressive aneurysm closure and retreatment rates in patients who have had balloon assisted coiling. Data is collected for 6 months after the procedure....

The purpose of this study if to further expand our knowledge of the Pipeline Embolization Device for treatment of an intracranial aneurysm....

People with Thyroid Eye Disease (TED) experience eye problems often associated with an overactive thyroid (Graves' disease). The eye problems seen with TED include swelling, redness and discomfort of the eyelids and eye surface, increased tearing, thickening and pulling back of the eyelids, bulging of...

Researchers at the Medical College of Wisconsin are studying what kind of modifications to one’s genetic code would lead to high blood pressure. We are looking to enroll identical twins who would have same genetic code, however, with different levels of blood pressure. This would...

Researchers at the Medical College of Wisconsin are studying causes of Degenerative Disc Disease (DDD). DDD is not really a disease but a term used to describe the normal changes in the spinal discs as you age. MRI techniques now allow scientists to view the...